Publications

    Since 2004
  1. Zhu Y, Mohapatra S, Weisshaar JC (2019) Rigidification of the Escherichia coli cytoplasm by the human antimicrobial peptide LL-37 revealed by superresolution fluorescence microscopy. PNAS. doi.org/10.1073/pnas.1814924116
  2. Mohapatra S, Weisshaar JC (2018) Modified Pearson correlation coefficient for two-color imaging in spherocylindrical cells. BMC Bioinformatics. doi:10.1186/s12859-018-2444-3
  3. Mohapatra S, Weisshaar JC (2018) Functional mapping of the E. coli translational machinery using single‐molecule tracking. Mol. Microbiol. doi:10.1111/mmi.14103
  4. Yang Z, Weisshaar JC (2018) HaloTag Assay Suggests Common Mechanism of E. coli Membrane Permeabilization Induced by Cationic Peptides. ACS Chemical Biology doi:10.1021/acschembio.8b00336
  5. Agrawal A, Weisshaar JC (2018) Effects of alterations of the E. coli lipopolysaccharide layer on membrane permeabilization events induced by Cecropin A. Biochimica et Biophysica acta https://doi.org/10.1016/j.bbamem.2018.04.009
  6. Yang Z, Choi H, Weisshaar JC (2018) Melittin-Induced Permeabilization, Re-sealing, and Re-permeabilization of E. coli Membranes. Biophysical Journal doi:10.1016/j.bpj.2017.10.046
  7. Mustafi M, Weisshaar JC (2018) Simultaneous Binding of Multiple EF-Tu Copies to Translating Ribosomes in Live Escherichia coli. mBio https://doi.org/10.1128/mBio.02143-17
  8. Choi H, Yang Z, Weisshaar JC. (2017) Oxidative stress induced in E. coli by the human antimicrobial peptide LL-37. Plos Pathogens doi.org/10.1371/journal.ppat.1006481
  9. Mohapatra S, Choi H, Ge X, Sanyal S, Weisshaar JC. (2017) Spatial Distribution and Ribosome-binding Dynamics of EF-P in Live E. coli. mBio doi: 10.1128/mBio.00300-17
  10. Barns KJ, Weisshaar JC. (2016) Single-cell, time-resolved study of the effects of the antimicrobial peptide alamethicin on Bacillus subtilis. Biochimica et Biophysica acta.  doi:10.1016/j.bbamem.2016.01.003
  11. Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC. (2015) Single-Cell, Time-Resolved Antimicrobial Effects on a Highly Cationic, Random Nylon-3 Copolymer on Live Escherichia coli. ACS Chemical Biology. 10.1021/acschembio.5b00547
  12. Choi H, Rangarajan N, Weisshaar JC. (2015) Lights, Camera, Action! Antimicrobial Peptide Mechanisms Imaged in Space and Time. Trends in Microbiology. doi:10.1016/j.tim.2015.11.004
  13. Li W, Bouveret E, Zhang Y, K Liu, Wang J, Weisshaar JC. (2015) Effects of Amino Acid Starvation on RelA Diffusive Behavior in Live Escherichia coli. Molecular Microbiology. 10.1111/mmi.13252
  14. Bakshi S, Choi H, Weisshaar JC. (2015) The Spatial Biology of Transcription and Translation in Rapidly Growing Escherichia coli. Frontiers in Microbiology. 10.3389/fmicb.2015.00636
  15. Choi H, Yang Z, Weisshaar JC. (2015) Single-Cell, Real-time Detection of Oxidative Stress Induced in E. coli by the Antimicrobial Peptide CM15. Proceedings in National Academy of Sciences. 10.1073/pnas.1417703112
  16. Bakshi S, Choi H, Mondal J, Weisshaar JC. (2014) Time-dependent effects of transcription-and translation-halting drugs on the spatial distributions of the Escherichia coli chromosome and ribosomes. Molecular Microbiology.94 (4).871-887. 10.1111/mmi.12805 
  17. Bakshi S, Choi H, Rangarajan N, Barns KJ, Weisshaar JC. (2014) Non-perturbative Imaging of Nuceloid Morphology in Live Bacterial Cells during Antimicrobial Peptide Attack. Applied and Environmental Microbiology. 00989-14. 10.1128/AEM.00989-14
  18. Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC. (2014) Medium Effects on Minimum Inhibitory Concentrations of Nylon-3 Polymers against E. coli. Plos One. 9 (8). e104500. 10.1371/journal.pone.0104500
  19. Bakshi S, Li W, Dalrymple RM, Choi H, Weisshaar JC. (2013) Partitioning of RNA Polymerase Activity in Live E. coli from Analysis of Single-molecule Diffusive Trajectories. Biophysical Journal. 105 (12):2676–2686. 10.1016/j.bpj.2013.10.024
  20. Rangarajan N, Bakshi S, Weisshaar JC. (2013). Localized Permeabilization of E. coli Membranes by the Antimicrobial Peptide Cecropin A. Biochemistry 52 (38):6584-6594. 10.1021/bi400785j
  21. Barns KJ, Weisshaar, JC. (2013). Real-time Attack of LL-37 on Single Bacillus subtilis Cells. Biochim. Biophys. Acta. 1828:1511-1520.doi:10.1016/j.bbamem.2013.02.011
  22. Bakshi S, Siryaporn A, Goulian M ,Weisshaar JC. (2012). Superresolution imaging of ribosomes and RNA polymerase in Escherichia coli cells. Mol Microbiol. 85:21-36. doi:10.1111/j.1365-2958.2012.08081.x  
  23. Bakshi S, Bratton BP, Weisshaar JC. (2011). Subdiffraction-Limit Study of Kaede Diffusion and Spatial Distribution in Live Escherichia coli. Biophys J. 101:2535-2544 di:10.1016/j.bpj.2011.10.013
  24. Bratton BP, Mooney RA, Weisshaar JC. (2011). Spatial Distribution and Diffusive Motion of RNA Polymerase in Live Escherichia coli. J. Bacteriol. 193:5138-5146 doi:10.1128/JB.00198-11
  25. Mondal J, Bratton BP, Li Y, Yethiraj A, Weisshaar JC. (2011). Entropy-Based Mechanism of Ribosome-Nucleoid Segregation in E. coli cells  . Biophys J. 100:2605-2613 doi:10.1016/j.bpj.2011.04.030
  26. Smith EA, Weisshaar JC. (2011). Docking, Not Fusion, as the Rate-Limiting Step in a SNARE-Deriven Vesicle Fusion Assay. Biophys J. 100:2141-2150 doi:10.1016/j.bpj.2011.03.015
  27. Sochacki KA, Barns KJ, Bucki R, Weisshaar JC. (2011). Real-time Attack on Single Escherichia coli cells by human antimicrobial peptide LL-37. PNAS. 108: E77-81. doi:10.1073/pnas.1101130108
  28. Sochacki KA, Shkel IA, Record MT, Weisshaar JC. (2011). Protein Diffusion in the Periplasm of E. coli under Osmotic Stress. Biophys J. 100: 22-31. doi:10.1016/j.bpj.2010.11.044
  29. Wang T, Ingram CJ, Weisshaar JC. (2010). Model Lipid Membrane with Facile Diffusion of Lipids and Integral Membrane Proteins. Langmuir. 26: 11157-11164.doi:10.1021/la101046r
  30. Wang T, Smith EA, Chapman ER, Weisshaar JC. (2009). Lipid Mixing and Content Release in Single-Vesicle, SNARE-Driven Fusion Assay with 1-5 ms Resolution. Biophys. J. 96: 4122-4131. doi:10.1016/j.bpj.2009.02.050
  31. Konopka MC, Sochacki KA, Bratton BP, Shkel IA, Record MT Jr., Weisshaar JC. (2009). Cytoplasmic Protein Mobility in Osmotically Stressed Escherichia coli. J Bacteriol. 191: 231-237. doi:10.1128/JB.00536-08
  32. Liu T, Wang T, Chapman ER, Weisshaar JC. (2008). Productive Hemifusion Intermediates in Fast Vesicle Fusion Driven by Neuronal SNAREs. Biophys. J. 94: 1303-1314. doi:10.1529/biophysj.107.107896
  33. Yethiraj A, Weisshaar JC. (2007). Why Are Lipid Rafts Not Observed In Vivo? Biophys. J. 93: 3113-3119. doi:10.1529/biophysj.106.101931
  34. Konopka MC, Weisshaar JC, Record MT Jr. (2007). Methods of changing biopolymer volume fraction and cytoplasmic solute concentrations for in vivo biophysical studies. Methods Enzymol. 428: 487-504. doi:10.1016/S0076-6879(07)28027-9
  35. Konopka MC, Shkel IA, Cayley S, Record MT Jr., Weisshaar JC. (2006). Crowding and Confinement Effects on Protein Diffusion In Vivo. J Bacteriol. 188: 6115-6123. doi:10.1128/JB.01982-05
  36. Liu T, Tucker WC, Bhalla A, Chapman ER, Weisshaar JC. (2005). SNARE-Driven, 25-Millisecond Vesicle Fusion In Vitro. Biophys J. 89: 2458-2472. i:10.1529/biophysj.105.062539
  37. Konopka MC, Weisshaar JC. (2004). Heterogeneous Motion of Secretory Vesicles in the Actin Cortex of Live Cells: 3D Tracking to 5-nm Accuracy. J Phys Chem A. 108: 9814-9826. doi:10.1021/jp048162v